SERPINE1
Chronic kidney disease stage 5
0.210
Therapeutic
RGD
An integrated lipidomics and metabolomics reveal nephroprotective effect and biochemical mechanism of Rheum officinale in chronic renal failure.
26903149 2016
×
Entrez Id: 2057
Gene Symbol: EPOR
EPOR
Chronic kidney disease stage 5
0.200
Biomarker
RGD
Down-Regulation of Cardiac Erythropoietin Receptor and its Downstream Activated Signal Transducer Phospho-STAT-5 in a Rat Model of Chronic Kidney Disease.
27468524 2016
×
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Chronic kidney disease stage 5
0.300
Biomarker
RGD
Changes of adiponectin and its receptors in rats following chronic renal failure.
24028144 2014
×
Entrez Id: 51094
Gene Symbol: ADIPOR1
ADIPOR1
Chronic kidney disease stage 5
0.230
Biomarker
RGD
Changes of adiponectin and its receptors in rats following chronic renal failure.
24028144 2014
×
Entrez Id: 79602
Gene Symbol: ADIPOR2
ADIPOR2
Chronic kidney disease stage 5
0.210
Biomarker
RGD
Changes of adiponectin and its receptors in rats following chronic renal failure.
24028144 2014
×
Entrez Id: 5741
Gene Symbol: PTH
PTH
Chronic kidney disease stage 5
0.300
Biomarker
RGD
Two novel vitamin D receptor modulators with similar structures exhibit different hypercalcemic effects in 5/6 nephrectomized uremic rats.
23548814 2013
×
Entrez Id: 664
Gene Symbol: BNIP3
BNIP3
Chronic kidney disease stage 5
0.200
Biomarker
RGD
Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach.
24090408 2013
×
Entrez Id: 6582
Gene Symbol: SLC22A2
SLC22A2
Chronic kidney disease stage 5
0.200
Biomarker
RGD
Renal uptake of substrates for organic anion transporters Oat1 and Oat3 and organic cation transporters Oct1 and Oct2 is altered in rats with adenine-induced chronic renal failure .
23280877 2013
×
Entrez Id: 8678
Gene Symbol: BECN1
BECN1
Chronic kidney disease stage 5
0.200
Biomarker
RGD
Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach.
24090408 2013
×
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Chronic kidney disease stage 5
0.280
Biomarker
RGD
Curcumin and enalapril ameliorate renal failure by antagonizing inflammation in 5/6 nephrectomized rats: role of phospholipase and cyclooxygenase.
22031851 2012
×
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
Chronic kidney disease stage 5
0.230
Therapeutic
RGD
[Effects of shenshuai II recipe on the protein expressions of Ang II and nNOS in chronic renal failure rats' nephridial tissue].
23185775 2012
×
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
Chronic kidney disease stage 5
0.200
Biomarker
RGD
Vascular insulin resistance related to endoplasmic reticulum stress in aortas from a rat model of chronic kidney disease.
22942179 2012
×
Entrez Id: 4023
Gene Symbol: LPL
LPL
Chronic kidney disease stage 5
0.200
Biomarker
RGD
Lipoprotein lipase deficiency in chronic kidney disease is accompanied by down-regulation of endothelial GPIHBP1 expression.
22009636 2012
×
Entrez Id: 2147
Gene Symbol: F2
F2
Chronic kidney disease stage 5
0.200
Therapeutic
RGD
5/6 nephrectomy as a validated rat model mimicking human warfarin-related nephropathy.
22473220 2012
×
Entrez Id: 10631
Gene Symbol: POSTN
POSTN
Chronic kidney disease stage 5
0.200
Biomarker
RGD
Periostin: novel tissue and urinary biomarker of progressive renal injury induces a coordinated mesenchymal phenotype in tubular cells.
22167593 2012
×
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
Chronic kidney disease stage 5
0.200
Therapeutic
RGD
Delayed mTOR inhibition with low dose of everolimus reduces TGFβ expression, attenuates proteinuria and renal damage in the renal mass reduction model.
22427849 2012
×
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
Chronic kidney disease stage 5
0.200
Biomarker
RGD
Inhibition of mineralocorticoid receptor is a renoprotective effect of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor pitavastatin.
21119529 2011
×
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Chronic kidney disease stage 5
0.280
Biomarker
RGD
Multiple antioxidants and L-arginine modulate inflammation and dyslipidemia in chronic renal failure rats.
20199183 2010
×
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
Chronic kidney disease stage 5
0.260
Biomarker
RGD
Erythropoietin regulates intestinal iron absorption in a rat model of chronic renal failure.
20631677 2010
×
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
Chronic kidney disease stage 5
0.210
Biomarker
RGD
High-calorie diet with moderate protein restriction prevents cachexia and ameliorates oxidative stress, inflammation and proteinuria in experimental chronic kidney disease.
20820841 2010
×
Entrez Id: 596
Gene Symbol: BCL2
BCL2
Chronic kidney disease stage 5
0.210
Therapeutic
RGD
Epoetin delta as an antifibrotic agent in the remnant kidney rat: a possible role for transforming growth factor beta and hepatocyte growth factor.
20424483 2010
×
Entrez Id: 847
Gene Symbol: CAT
CAT
Chronic kidney disease stage 5
0.200
Biomarker
RGD
Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure.
20007347 2010
×
Entrez Id: 38
Gene Symbol: ACAT1
ACAT1
Chronic kidney disease stage 5
0.200
Biomarker
RGD
Niacin improves renal lipid metabolism and slows progression in chronic kidney disease.
19878707 2010
×
Entrez Id: 10
Gene Symbol: NAT2
NAT2
Chronic kidney disease stage 5
0.200
Biomarker
RGD
Down-regulation of liver drug-metabolizing enzymes in a murine model of chronic renal failure.
20007296 2010
×
Entrez Id: 9817
Gene Symbol: KEAP1
KEAP1
Chronic kidney disease stage 5
0.200
Biomarker
RGD
Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure .
20007347 2010